Details for gene set CL2170, U2-TYPE CATALYTIC STEP 2 SPLICEOSOME, AND SPLICEOSOMAL CONFORMATIONAL CHANGES TO GENERATE CATALYTIC CONFORMATION[GSEA]

Table: GSEA Results Summary

Dataset	Chronic fatigue syndrome__20002-both_sexes-1482
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	CL2170, U2-TYPE CATALYTIC STEP 2 SPLICEOSOME, AND SPLICEOSOMAL CONFORMATIONAL CHANGES TO GENERATE CATALYTIC CONFORMATION
Enrichment Score (ES)	0.6485894
Normalized Enrichment Score (NES)	1.119141
Nominal p-value	0.22122122
FDR q-value	0.69868475
FWER p-Value	1.0

Fig 1: Enrichment plot: CL2170, U2-TYPE CATALYTIC STEP 2 SPLICEOSOME, AND SPLICEOSOMAL CONFORMATIONAL CHANGES TO GENERATE CATALYTIC CONFORMATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PRPF8	150	2.539	0.2830	Yes
2	PLRG1	841	1.611	0.4294	Yes
3	CRNKL1	1630	1.124	0.5146	Yes
4	SNRNP40	2484	0.770	0.5555	Yes
5	SYF2	2554	0.744	0.6370	Yes
6	DHX38	3418	0.519	0.6486	Yes
7	PPIE	5704	0.248	0.5500	No
8	CWC25	8870	0.123	0.3880	No
9	YJU2	8890	0.122	0.4010	No
10	PPIL1	9311	0.111	0.3904	No
11	BCAS2	9360	0.110	0.4003	No
12	XAB2	9672	0.104	0.3949	No
13	CWC22	9852	0.100	0.3964	No
14	SNRNP200	10420	0.090	0.3751	No
15	SNW1	11064	0.078	0.3483	No
16	AQR	11182	0.076	0.3506	No
17	ISY1	11776	0.067	0.3253	No
18	ISY1-RAB43	11778	0.067	0.3330	No
19	CDC40	12396	0.059	0.3054	No
20	BUD31	14089	0.034	0.2153	No
21	RBM22	14456	0.019	0.1971	No
22	CDC5L	14879	-0.000	0.1736	No
23	EFTUD2	15165	-0.000	0.1578	No
24	SNRPA1	15729	-0.000	0.1265	No

Fig 2: CL2170, U2-TYPE CATALYTIC STEP 2 SPLICEOSOME, AND SPLICEOSOMAL CONFORMATIONAL CHANGES TO GENERATE CATALYTIC CONFORMATION: Random ES distribution
Gene set null distribution of ES for CL2170, U2-TYPE CATALYTIC STEP 2 SPLICEOSOME, AND SPLICEOSOMAL CONFORMATIONAL CHANGES TO GENERATE CATALYTIC CONFORMATION